In the 1760s, a Scottish doctor named William Stark, evidently encouraged by Benjamin Franklin, conducted a series of patently foolhardy experiments in which he tried to identify the active agent by, somewhat bizarrely, depriving himself of it. For weeks he lived on only the most basic of foods – bread and water chiefly – to see what would happen. What happened was that in just over six months he killed himself, from scurvy, without coming to any helpful conclusions at all.