The bitter irony was that Franklin had become a fervent advocate of smallpox vaccinations after they had been ridiculed in the New England Courant when Franklin worked there for his brother. In the years preceding Franky’s birth, he had editorialized in the Pennsylvania Gazette in support of inoculations and published statistics showing how effective they were. In 1730, for example, he wrote an account of a Boston epidemic in which most people who had been vaccinated were spared.